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A Small Molecule Inhibitor of IkB-Kinase is Selectively Toxic for Subgroups of
Diffuse Large B Cell Lymphoma Defined by Gene Expression Profiling
Lloyd T. Lam§, R. Eric Davis§, Jackie Pierce*+, Michael Hepperle*, Yajun Xu*, M
aria Hottelet*, Yuhua Nong*, Danyi Wen*, Julian Adams*#, Lenny Dang*, and Louis
M. Staudt§
§Metabolism Branch
Center for Cancer Research
National Cancer Institute
National Institutes of Health
Bethesda, Maryland 20892
*Millennium Pharmaceuticals
Cambridge, MA 02138
+Present address: Merck Research Laboratories
#Present address: Infinity Pharmaceuticals, Inc.
Cambridge, MA 02139
Corresponding author:
Louis M. Staudt, MD, PhD
9000 Rockville Pike
Building 10, Room 5A/02
Bethesda, MD 20892
301-402-1892
Fax: 301-496-9956
email: lstaudt@mail.nih.gov
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