WEB Table 2. Target gene
consistency across experimental systems
|
Gene Name |
Blimp-1 target in # of Array Systems |
Confirmed by Independent Assay |
|
A1, Bcl-2 related protein |
2 |
yes |
|
AID |
1 |
yes |
|
BCL-6 |
3 |
yes |
|
BLNK |
2 |
yes |
|
btk |
2 |
yes |
|
CD11A |
2 |
yes |
|
CD19 |
2 |
yes |
|
CD20 |
6 |
yes |
|
CD22 |
4 |
yes |
|
CD27 |
1 |
yes |
|
CD37 |
6 |
yes |
|
CD45 |
3 |
yes |
|
CD53 |
5 |
yes |
|
CD79A |
3 |
yes |
|
CD83 |
3 |
yes |
|
CD86 |
2 |
yes |
|
CIITA |
2 |
yes |
|
c-myc |
4 |
yes |
|
CXCR5 |
1 |
yes |
|
DNA-PKcs |
3 |
yes |
|
EBF |
1 |
yes |
|
ICSBP |
3 |
yes |
|
Id3 |
4 |
yes |
|
Immunoglobulin J chain |
1 |
yes |
|
JAW1 |
5 |
yes |
|
Ku86 |
2 |
yes |
|
LyGDI |
3 |
yes |
|
MHC Class II, DM alpha |
3 |
yes |
|
MHC Class II, DM beta |
3 |
yes |
|
MHC Class II, DN alpha |
1 |
yes |
|
MHC Class II, DP alpha |
2 |
yes |
|
MHC Class II, DP beta |
1 |
yes |
|
MHC Class II, DQ alpha |
3 |
yes |
|
MHC Class II, DR alpha |
4 |
yes |
|
MHC Class II, DR beta |
4 |
yes |
|
Napsin 2 |
7 |
yes |
|
OCT_2 |
4 |
yes |
|
Pax5 |
1 |
yes |
|
Spi-B |
4 |
yes |
|
STAT6 |
5 |
yes |
|
syk |
4 |
yes |
|
XBP-1 |
1 |
yes |
|
14.3.3 protein |
3 |
|
|
2'-5' oligoadenylate synthetase E |
3 |
|
|
4-1BB ligand |
2 |
|
|
A20 |
2 |
|
|
ABF-1 |
2 |
|
|
Acidic nuclear phosphoprotein pp32 |
2 |
|
|
Adenylosuccinate synthase |
1 |
|
|
AIM2 |
1 |
|
|
Akt2 kinase |
1 |
|
|
A-myb |
1 |
|
|
APR |
1 |
|
|
Arachidonate 5-lipoxygenase |
2 |
|
|
Arp2/3 complex subunit p34-Arc |
2 |
|
|
ATPase, Ca++ transporting, ubiquitous |
1 |
|
|
aurora/IPL1-related kinase |
2 |
|
|
B-actin |
2 |
|
|
BAF53a |
2 |
|
|
BANP |
4 |
|
|
BCKDH |
3 |
|
|
BCL11A-XL |
2 |
|
|
BCL-7A |
3 |
|
|
beta-2-microglobulin |
5 |
|
|
beta-galactoside alpha-2 3-sialyltransferase |
1 |
|
|
B-myb |
3 |
|
|
BRDG-1 |
2 |
|
|
cam kinase I |
1 |
|
|
catalase |
1 |
|
|
cathepsin B |
1 |
|
|
cathepsin S |
1 |
|
|
CD103 beta |
2 |
|
|
CD21 |
1 |
|
|
CD23A |
1 |
|
|
CD24 |
2 |
|
|
CD36-like 1 |
2 |
|
|
CD44 |
2 |
|
|
CD52 |
1 |
|
|
CD54, ICAM-1 |
2 |
|
|
CD68 |
2 |
|
|
CD69 |
1 |
|
|
CD75 |
1 |
|
|
CD97 |
2 |
|
|
CDC2 homolog |
3 |
|
|
CDC21 homolog |
1 |
|
|
CDC37 homolog |
2 |
|
|
CDC47 homolog |
3 |
|
|
cdk2 |
2 |
|
|
cell cycle p38-2G4 homolog |
3 |
|
|
Choline kinase |
1 |
|
|
CIN85, c-Cbl-interacting protein |
1 |
|
|
CIP4, Cdc42-interacting protein 4 |
1 |
|
|
ckshs1 |
2 |
|
|
ckshs2 |
1 |
|
|
CLPP, ATP-dependent Clp proteinase |
2 |
|
|
complement component C5 |
2 |
|
|
coronin-like protein p57 |
3 |
|
|
csk |
4 |
|
|
cysteine protease |
1 |
|
|
cytoskeletal gamma-actin |
2 |
|
|
D123 |
2 |
|
|
Daxx |
3 |
|
|
dek |
2 |
|
|
DHFR |
1 |
|
|
DIFF48 |
1 |
|
|
DNA (cytosine-5-)-methyltransferase |
3 |
|
|
DNA polymerase delta2 (50kD) |
2 |
|
|
DNA primase (subunit p48) |
1 |
|
|
dUTP pyrophosphatase |
3 |
|
|
E2A |
2 |
|
|
E2F-1 |
2 |
|
|
EBI3 |
2 |
|
|
eIF2 subunit 2 |
3 |
|
|
eIF4E binding protein 1 |
3 |
|
|
endonuclease III homolog |
3 |
|
|
ERF-1 |
1 |
|
|
Exosome component Rrp46, exoribonuclease |
1 |
|
|
FCERI |
2 |
|
|
Ferritin heavy chain |
2 |
|
|
Ferritin light chain |
2 |
|
|
FLI-1 |
3 |
|
|
fyn |
2 |
|
|
G beta 1 |
3 |
|
|
G beta 2 |
2 |
|
|
G protein-linked receptor, GPCR W |
5 |
|
|
GADD153, CHOP |
1 |
|
|
GADD45 beta |
1 |
|
|
GALECTIN-1 |
1 |
|
|
gamma-IFN inducible gene IP-30 |
3 |
|
|
Gi2 protein alpha |
2 |
|
|
GLUT5 |
3 |
|
|
Glutamic-oxaloacetic transaminase 2 |
3 |
|
|
Glutathione-S-transferase pi-1 |
3 |
|
|
glycogen synthase kinase 3 |
2 |
|
|
Gs alpha |
2 |
|
|
guanosine 5'-monophosphate synthase |
2 |
|
|
HEM45 |
2 |
|
|
HHR23B, XPC p58 |
3 |
|
|
Histone H2A.2 |
1 |
|
|
HNPP |
3 |
|
|
HPH2 |
3 |
|
|
HRC1 |
1 |
|
|
HSP70 |
2 |
|
|
Id2 |
3 |
|
|
IFI16 |
4 |
|
|
IFN-gamma receptor alpha chain |
1 |
|
|
IFN-induced 17 KD protein |
2 |
|
|
IFN-induced protein 1-8D |
2 |
|
|
IFN-inducible protein 9-27 |
2 |
|
|
Ig kappa light chain |
5 |
|
|
Ig lambda light chain |
3 |
|
|
IgG Fc receptor |
2 |
|
|
IgG3 heavy chain constant region |
1 |
|
|
Ig-related 14.1 |
1 |
|
|
Ikaros |
3 |
|
|
IkB alpha |
3 |
|
|
IL-10 |
1 |
|
|
IL-13 receptor alpha2 |
2 |
|
|
IL-16, Lymphocyte chemoattractant factor |
1 |
|
|
IL-8 |
2 |
|
|
importin beta subunit |
2 |
|
|
invariant chain |
6 |
|
|
IP-10 |
2 |
|
|
IRF-3 |
2 |
|
|
IRTA1a |
1 |
|
|
IRTA2a |
1 |
|
|
JkR1 |
2 |
|
|
jun-B |
1 |
|
|
Ku70 |
2 |
|
|
L-3-hydroxyacyl-CoA DH |
2 |
|
|
Lactate dehydrogenase A |
1 |
|
|
LAF-4 |
2 |
|
|
lck |
2 |
|
|
LDH-B |
1 |
|
|
leukemia associated gene 2 |
2 |
|
|
Low-affinity IgG Fc receptor II-B and C |
3 |
|
|
L-plastin |
5 |
|
|
lyn |
2 |
|
|
lysophospholipase homolog (HU-K5) |
2 |
|
|
LYSP100 |
2 |
|
|
M17 homolog, GC-restricted gene |
2 |
|
|
Malate oxidoreductase |
1 |
|
|
MAT-1 homolog |
2 |
|
|
MCM2=DNA replication licensing factor |
2 |
|
|
MCP-1 |
2 |
|
|
MEK1 |
2 |
|
|
MIP-1 alpha |
2 |
|
|
MIP-1 beta |
1 |
|
|
MKP-1, MAP kinase phosphatase 1 |
1 |
|
|
MMP-1 |
1 |
|
|
MMP-2 |
2 |
|
|
Myosin class I |
1 |
|
|
myosin-IC |
1 |
|
|
Myt1 kinase |
3 |
|
|
NAD-dep't methyleneTHF DH |
3 |
|
|
NIX |
3 |
|
|
nucleophosmin |
3 |
|
|
OBF-1 |
1 |
|
|
ornithine decarboxylase 1 |
3 |
|
|
osteopontin |
4 |
|
|
p18-INK6 |
1 |
|
|
p21-WAF1 |
1 |
|
|
p53 inducible protein (PIR121) |
3 |
|
|
p55CDC |
2 |
|
|
PAG |
1 |
|
|
PARP |
3 |
|
|
PBEF |
1 |
|
|
PC4, RNA polymerase II coactivator |
2 |
|
|
PCNA |
3 |
|
|
Phosphatidylserine synthase I |
3 |
|
|
Phosphorylase kinase, gamma 2 chain |
3 |
|
|
PKC beta |
3 |
|
|
Pleckstrin |
5 |
|
|
pLK |
3 |
|
|
PMS4 |
2 |
|
|
PP5, serine-threonine phosphatase |
2 |
|
|
Proteasome (prosome macropain) LMP-7 |
2 |
|
|
Proteasome-like subunit (MECL-1) |
5 |
|
|
protein kinase (MLK-3) |
1 |
|
|
Proteosome LMP-2 |
3 |
|
|
protocadherin 43 |
1 |
|
|
RANTES |
1 |
|
|
RAP-1B |
2 |
|
|
RB |
3 |
|
|
Rcl, c-Myc-responsive protein |
2 |
|
|
Receptor protein-tyrosine kinase EDDR1 |
2 |
|
|
RGS13 |
3 |
|
|
Ribosomal protein S6 kinase 90kD |
2 |
|
|
RP105 |
1 |
|
|
RPA1 (70kD) |
3 |
|
|
S100 Ca++ binding protein A4 |
5 |
|
|
serine/threonine kinase EMK |
1 |
|
|
SHC signaling adaptor protein |
1 |
|
|
SHP-1 |
2 |
|
|
SIAH-2 |
3 |
|
|
SIP-110 |
1 |
|
|
Sox4 |
1 |
|
|
spi-1 |
2 |
|
|
SRE binding protein-2 |
3 |
|
|
TANK, I-TRAF |
1 |
|
|
TGF-beta inducible EGR alpha |
1 |
|
|
thymosin beta-4 |
6 |
|
|
Tis11d |
1 |
|
|
Toll-like receptor 1 |
1 |
|
|
Toll-like receptor 10 |
1 |
|
|
TRAF1 |
1 |
|
|
TRAF5 |
2 |
|
|
Transcription elongation factor B (SIII) |
2 |
|
|
TTF, rhoH |
1 |
|
|
TTG-2, Rhombotin-2 |
1 |
|
|
tubulin-beta |
3 |
|
|
tubulin-gamma |
2 |
|
|
UCP2 |
3 |
|
|
uridine phosphorylase |
3 |
|
|
Vanin-2 |
2 |
|
|
VDUP1 |
2 |
|
|
VEGF |
2 |
|
|
VPREB3 |
1 |
|
|
WIP, WASP interacting protein |
3 |
|
|
XIAP |
2 |
|