|
Figure A. Signal transduction in T
cells: mutations identified in severe combined immunodeficiency
(SCID) and combined immunodeficiency (CID) patients. |
|
Figure B. Partial, but unspecific, reconstitution of
Ca2+ influx in the presence of high extracellular Ca2+ and ionomycin
concentrations. |
|
Figure C. No systematic differences
in resting membrane potential and depolarisation in SCID T cells
as compared to normal controls. |
|
Figure D. Synthesis of multiple cytokine
and inducible genes is strongly reduced or absent in SCID T cells. |
